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Lymphangioleiomyomatosis
- Often by premenopausal patients, but also (rarer) in adolescence.The pulmonary manifestation is most common: pneumothorax, dyspnea.Abdominal symptoms include chronic complaints, abd...
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Optogenetics project takes top NIDA Addiction Science Award
- A project that maps dopamine circuits in the prefrontal cortex through optogenetic manipulation was given top honors in this year’s annual Addiction Science Awards at the 2012 Intel International Science and Engineering Fair (ISEF) -- the world's largest science competition for high school students. The awards were presented by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, and Friends of NIDA, a coalition that supports NIDA’s mission. The Intel ISEF Addiction Science Awards were presented at a ceremony Thursday night at the David L. Lawrence Convention Center in Pittsburgh.
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NIH-led study finds genetic test results do not trigger increased use of health services
- People have increasing opportunities to participate in genetic testing that can indicate their range of risk for developing a disease. Receiving these results does not appreciably drive up or diminish test recipients’ demand for potentially costly follow-up health services, according to a study performed by researchers at the National Institutes of Health and colleagues at other institutions.
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NIH study finds that coffee drinkers have lower risk of death
- Older adults who drank coffee -- caffeinated or decaffeinated -- had a lower risk of death overall than others who did not drink coffee, according a study by researchers from the National Cancer Institute (NCI), part of the National Institutes of Health, and AARP.
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Paralyzed individuals use thought-controlled robotic arm to reach and grasp
- In an ongoing clinical trial, a paralyzed woman was able to reach for and sip from a drink on her own -- for the first time in nearly 15 years -- by using her thoughts to direct a robotic arm. The trial, funded in part by the National Institutes of Health, is evaluating the safety and feasibility of an investigational device called the BrainGate neural interface system.
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NIH-funded research provides new clues on how ApoE4 affects Alzheimer's risk
- Common variants of the ApoE gene are strongly associated with the risk of developing late-onset Alzheimer's disease, but the gene's role in the disease has been unclear. Now, researchers funded by the National Institutes of Health have found that in mice, having the most risky variant of ApoE damages the blood vessels that feed the brain.
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NINR welcomes five new members to the National Advisory Council for Nursing Research
- The National Institute of Nursing Research (NINR) announces five new members to the National Advisory Council for Nursing Research (NACNR), the institute's principal advisory board. Members of the council are drawn from the scientific and lay communities, embodying a diverse perspective from the fields of nursing, public and health policy, law, and economics. NINR, a component of the National Institutes of Health, is the primary federal agency for the support of nursing research.
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NIH statement on HIV Vaccine Awareness Day - May 18, 2012
- There is a growing consensus that we can significantly curtail the HIV/AIDS pandemic by implementing scientifically proven HIV prevention strategies, such as voluntary medically supervised adult male circumcision, prevention of mother-to-child transmission and treatment as prevention.
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RFP Announcement: Nonhuman Primate Core Functional Genomics Laboratory for AIDS Vaccine Research and Development RFP NIAID-DAIDS-NIH-AI-2012-142
- Notice NOT-AI-12-031 from the NIH Guide for Grants and Contracts
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Technical Assistance Webinar for RFA-ES-12-001: Children's Environmental Health and Disease Prevention Research Centers (P01)
- Notice NOT-ES-12-011 from the NIH Guide for Grants and Contracts
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Notice of Correction to Application Due Date, Expiration Date, Funds Available and Award Budget for RFA-FD-12-021 Pharmacokinetics Studies of Tacrolimus in Transplant Patients (U01)
- Notice NOT-FD-12-010 from the NIH Guide for Grants and Contracts
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Notice of Intent to Publish a Funding Opportunity Announcement (FOA) for Women's Mental Health During Pregnancy and the Postpartum Period (R01)
- Notice NOT-MH-12-025 from the NIH Guide for Grants and Contracts
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Notice of Intent to Publish a Funding Opportunity Announcement (FOA) for Women's Mental Health During Pregnancy and the Postpartum Period (R21)
- Notice NOT-MH-12-026 from the NIH Guide for Grants and Contracts
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Request for Information (RFI): The National Database for Autism Research Challenge
- Notice NOT-MH-12-027 from the NIH Guide for Grants and Contracts
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Change in NINDS salary caps for the K02, K08 and K23 Career Development Awards
- Notice NOT-NS-12-018 from the NIH Guide for Grants and Contracts
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Final Weeks to Register for NIH Regional Seminar on Program Funding and Grants Administration in Washington, D.C. - June 20-22, 2012
- Notice NOT-OD-12-109 from the NIH Guide for Grants and Contracts
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Notice of NIH Piloting of Procedures for Special Council Review of Research Applications from PD(s)/PI(s) with More than $1.5 Million Total Annual NIH Support
- Notice NOT-OD-12-110 from the NIH Guide for Grants and Contracts
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Notice: Human Heredity and Health (H3Africa) Applicant Information Sessions in Africa
- Notice NOT-RM-12-022 from the NIH Guide for Grants and Contracts
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Synthesis and Preclinical Evaluation of Medications to Treat Substance Use Disorders (SUDs) (R01)
- Funding Opportunity RFA-DA-13-004 from the NIH Guide for Grants and Contracts. The National Institute on Drug Abuse (NIDA) is soliciting grant (R01) applications to support the synthesis and preclinical evaluation of new molecular entities as potential treatments for Substance Use Disorders (SUDs). Responsive applications may include synthesis, identification, optimization and preclinical efficacy and/or safety assessment of lead compounds. Applications must provide timelines and decision-trees with go/no-go criteria to advance or discontinue testing a compound. Possible new molecular entities include, but are not limited to, small molecules, enzymes, antibodies, and vaccines. The goal is to identify candidate compounds and advance them towards Investigational New Drug (IND) submission.
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Limited Competition for the Continuation of the Halt-Polycystic Kidney Disease Trials Data Coordinating Center (DCC) (U01)
- Funding Opportunity RFA-DK-12-505 from the NIH Guide for Grants and Contracts. The purpose of this limited competition is to extend the activities of the Data Coordinating Center (DCC) during the final two years of patient follow-up of the two ongoing HALT-Polycystic Kidney Disease (PKD) clinical trials. The extension will insure the statistical power and significance of the study outcomes. The HALT-PKD Trials are comprised of two studies (A and B) that are both fully enrolled. HALT-PKD Study A is evaluating the impact of renin-angiotensin-aldosterone system (RAAS) blockade on progression of disease in 548 hypertensive PKD patients with estimated glomerular filtration rate (GFR) 60ml/min/1.73 m2. The primary endpoint of the study is the percent change in total kidney volume, as measured by magnetic resonance imaging (MRI) over time. HALT-PKD Study B is evaluating the impact of RAAS blockade on progression of disease in 472 hypertensive PKD patients with estimated GFR 30-60 ml/min/1.73 m2. The primary endpoint of Study B is a composite endpoint of time to the 50% reduction of baseline estimated GFR, ESRD (initiation of dialysis or preemptive transplant), or death.
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Enhancing post-market surveillance through developing registries for medical device epidemiology (U01)
- Funding Opportunity RFA-FD-12-028 from the NIH Guide for Grants and Contracts. (1) To develop registries and consortia in key medical device areas to implement new registry methodologies that strategically broaden the scope of the US and international postmarket surveillance system, and (2) To address identified gaps in the current postmarket surveillance system by developing new methodologies for registry data collection and linkage, or by adapting known methodologies to medical devices, and (3) To develop novel methodology that allows for use of the registry data collection infrastructure to serve multiple purposes including postmarket surveillance, device tracking through Unique Device Identifiers (UDI), prospective embedded studies, quality improvement, and other uses.
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The NIH Centers for Accelerated Innovations (U54)
- Funding Opportunity RFA-HL-13-008 from the NIH Guide for Grants and Contracts. The NIH Centers for Accelerated Innovations (NCAI) will develop Centers that (1) solicit and select promising emerging technologies, such as therapeutics (e.g., drugs, biologics), preventatives, diagnostics, devices, tools, etc. and (2) facilitate their translation to commercialized products that improve patient care and enhance health. The NCAI will nurture the development of high priority early-stage technologies within the NHLBIs mission in a manner consistent with business case development and regulatory requirements by providing (1) funding for product definition studies (e.g. feasibility studies, prototype development, or proof-of-concept studies), (2) unified and coordinated access to expertise in areas required for early technology development, including scientific, regulatory, reimbursement, business, legal, and project management, and (3) training and hands-on experience in entrepreneurism. Establishing public-private partnerships and providing non-federal funds will be critical for success.
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Research Education Program for Laboratory Animal Medicine Veterinarians (R25)
- Funding Opportunity RFA-OD-12-006 from the NIH Guide for Grants and Contracts. This funding opportunity announcement issued by the Office of Research Infrastructure Programs (ORIP), Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI), Officer of the Director, NIH, solicits Research Education Grant (R25) applications to provide research education for veterinarians interested in pursuing a career in Laboratory Animal Medicine (LAM). The objective is to prepare veterinarians to be competent and proficient in the field of Laboratory Animal Medicine in support of biomedical investigations with emphasis on performing collaborative research, and development and maintenance of animal models in support of translational research activities.
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Transition to Independent Environmental Health Research (TIEHR) Career Development Award (K22)
- Funding Opportunity PA-12-188 from the NIH Guide for Grants and Contracts. The Transitions to Independent Environmental Health Research (TIEHR) Career Development Award is a 3-year bridge scholar development program for newly independent faculty who intend to pursue careers focused on environmental health sciences research. At the conclusion of the career development period the candidates are expected to demonstrate they can successfully compete for research funding in the environmental health sciences..
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National Institute on Aging Analysis of Alzheimer's Disease Genome Sequencing Project Data [U19]
- Funding Opportunity PAR-12-183 from the NIH Guide for Grants and Contracts. The National Institute on Aging invites applications specific to the analysis of whole exome and genome sequencing data provided by the National Human Genome Research Institute Large-Scale Sequencing Program for the Alzheimer's disease research community.
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Macroeconomic Aspects of Population Aging (R01)
- Funding Opportunity PAR-12-186 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites research on the macroeconomics of aging - the impact of population aging on the macroeconomy and in turn how macroeconomic factors impact health and well-being.
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NIGMS National Centers for Systems Biology (P50)
- Funding Opportunity PAR-12-187 from the NIH Guide for Grants and Contracts. The National Institute of General Medical Sciences (NIGMS) invites grant applications from institutions/organizations proposing to establish Centers of Excellence in Systems Biology. The goal of this initiative is to promote pioneering research, research training, education, and outreach programs focused on systems-level inquiries of biomedical phenomena within the NIGMS mission. The description of the NIGMS mission can be found on the website, www.nigms.nih.gov
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