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Lymphangioleiomyomatosis
- Often by premenopausal patients, but also (rarer) in adolescence.The pulmonary manifestation is most common: pneumothorax, dyspnea.Abdominal symptoms include chronic complaints, abd...
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Restricting calories early on does not help acute lung injury patients on ventilators
- Acute lung injury patients on ventilators who require a feeding tube have a similar number of ventilator-free hospital days and similar mortality rates if they receive a low-calorie feeding program initially followed by a full-calorie program compared to a full-calorie program right away. These results are part of a new clinical study funded by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.
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New, free e-biography released
- Always There: the Remarkable Life of Ruth Lillian Kirschstein, M.D., a new biography released Feb. 6, tells the rare story of a woman who was as comfortable conversing with lawmakers on Capitol Hill as she was bringing science to children in inner-city classrooms.
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New website: NIH Clinical Research Trials and You
- The National Institutes of Health has created a new website, NIH Clinical Research Trials and You to help people learn more about clinical trials, why they matter, and how to participate.
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Gene regulator in brain's executive hub tracked across lifespan -- NIH study
- For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain's executive hub. Among key findings of the study by National Institutes of Health scientists: genes implicated in schizophrenia and autism turn out to be members of a select club of genes in which regulatory activity peaks during an environmentally-sensitive critical period in development.
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NIH study uncovers probable mechanism underlying resveratrol activity
- National Institutes of Health researchers and their colleagues have identified how resveratrol, a naturally occurring chemical found in red wine and other plant products, may confer its health benefits.
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NCCAM's Advisory Council welcomes six new members
- The National Center for Complementary and Alternative Medicine (NCCAM) welcomes six new members to the National Advisory Council for Complementary and Alternative Medicine. The council serves as the principal advisory body to NCCAM, the lead federal agency for research on complementary medicine, and a component of the National Institutes of Health.
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The NIH urges women to protect their heart health
- As part of American Heart Month, on Wednesday, Feb. 8, 2012, the National Heart, Lung, and Blood Institute's (NHLBI's) The Heart Truth campaign, with the support of the Foundation for the National Institutes of Health (FNIH), will showcase its signature event, the Red Dress Collection 2012 at Mercedes-Benz Fashion Week in New York City.
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NIH-funded HIV clinical research sites to join pediatric tuberculosis vaccine study
- Several U.S. government-funded HIV/AIDS clinical research sites in Africa will join other collaborators in an ongoing clinical trial testing an investigational tuberculosis (TB) vaccine in infants at risk for TB infection. "We are pleased to be able to tap into our existing HIV/AIDS clinical research infrastructure to help test promising investigational vaccines against TB," said NIAID Director Anthony S. Fauci, M.D. The sites are funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
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Award-winning physician appointed deputy director at NIMHD
- The National Institute on Minority Health and Health Disparities (NIMHD) announced today the appointment of M. Roy Wilson, M.D., M.S., an award-winning physician and academic administrator, as NIMH's Deputy Director Strategic Scientific Planning and Program Coordination. NIMHD is part of the National Institutes of Health.
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New NIH fact sheet explains test for diabetes, prediabetes
- A new fact sheet from the National Institutes of Health explains the A1C test, a widely used and important test to diagnose type 2 diabetes and prediabetes, and to monitor blood glucose levels of people with type 1 and type 2 diabetes.
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NIH launches trials to evaluate CPR and drugs after sudden cardiac arrest
- The National Institutes of Health has launched two multi-site clinical trials to evaluate treatments for out-of-hospital cardiac arrest. One will compare continuous chest compressions (CCC) combined with pause- free rescue breathing to standard cardiopulmonary resuscitation (CPR), which includes a combination of chest compressions and pauses for rescue breathing. The other trial will compare treatment with the drug amiodarone, another drug called lidocaine, or neither medication (a salt-water placebo) in participants with shock-resistant ventricular fibrillation, a condition in which the heart beats chaotically instead of pumping blood.
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NIH Study shows caffeine consumption linked to estrogen changes
- Asian women who consumed an average of 200 milligrams or more of caffeine a day -- the equivalent of roughly two cups of coffee -- had elevated estrogen levels when compared to women who consumed less, according to a study of reproductive age women by researchers at the National Institutes of Health and other institutions.
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Elevated risk factors linked to major cardiovascular disease events across a lifetime
- In one of the largest-ever analyses of lifetime risks for cardiovascular disease (CVD), researchers have found that middle-aged adults who have one or more elevated traditional risk factors for CVD, such as high blood pressure, have a substantially greater chance of having a major CVD event, such as heart attack or stroke, during their remaining lifetime than people with optimal levels of risk factors. This National Institutes of Health-supported study used health data from 257,384 people and was the first to look simultaneously at multiple risk factors for CVD across age, sex, race, and birth generation.
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High animal fat diet increases gestational diabetes risk
- Women who consumed a diet high in animal fat and cholesterol before pregnancy were at higher risk for gestational diabetes than women whose diets were lower in animal fat and cholesterol, according to researchers at the National Institutes of Health and Harvard University.
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NIH kidney disease experts urge: Get Involved
- A new series of free tools and resources will help community groups increase awareness about steps to prevent kidney disease or improve management. The online resource is sponsored by the National Institutes of Health's National Kidney Disease Education Program (NKDEP).
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Treatment of silent acid reflux does not improve asthma in children, NIH study finds
- Adding the acid reflux drug lansoprazole to a standard inhaled steroid treatment for asthma does not improve asthma control in children who have no symptom of acid reflux, according to a new study funded in part by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health.
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Notice of Intent to Publish a Request for Applications for Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Centers (U54)
- Notice NOT-AR-13-002 from the NIH Guide for Grants and Contracts
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Request for Information (RFI): Optimization of Information Technology for Biobanks Collecting Specimens from Clinical Trials Sponsored by the National Cancer Institute (NCI)
- Notice NOT-CA-12-008 from the NIH Guide for Grants and Contracts
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Notice of Corrections for PAR-12-085 NIBIB Research Education Programs for Residents and Clinical Fellows (R25)
- Notice NOT-EB-12-002 from the NIH Guide for Grants and Contracts
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Request for Information (RFI): Updating the National Institutes of Health Research Plan on Fragile X Syndrome and Associated Disorders
- Notice NOT-HD-12-012 from the NIH Guide for Grants and Contracts
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Salary Limitation on FY2012 AHRQ Grants, Cooperative Agreements, and Contracts
- Notice NOT-HS-12-007 from the NIH Guide for Grants and Contracts
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Findings of Research Misconduct
- Notice NOT-OD-12-046 from the NIH Guide for Grants and Contracts
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Ancillary Domain Validation Patient-Reported Outcomes Measurement Information System (PROMIS) Studies (R01)
- Funding Opportunity RFA-AR-12-007 from the NIH Guide for Grants and Contracts. With this Funding Opportunity Announcement (FOA), the NIH solicits applications that propose to conduct ancillary studies intended to facilitate incorporation of PROMIS (Patient-Reported Outcomes Measurement Information System) domains into ongoing clinical projects in patient populations that represent the NIH portfolio of diseases (http://www.nih.gov). The ongoing project can be a clinical trial, observational study or patient care population that can provide a sufficient cohort of well-characterized patients and has an existing infrastructure that can facilitate data collection and subsequent analysis. In particular, NIH invites applications focusing on outcomes research to use PROMIS domains and encourages collaborative approaches and data-sharing with the PROMIS Network contributing to the further validation, testing, and evaluation of the existing PROMIS item banks in these populations.
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Phased Services Research Studies of Drug Use Prevention, Addiction Treatment, and HIV in an Era of Health Care Reform (R21/R33)
- Funding Opportunity RFA-DA-13-001 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) solicits applications for Phased Innovation (R21/R33) research projects to conduct rigorous, objective services research to monitor and examine changes in drug use prevention, addiction treatment, and associated HIV and viral hepatitis services, that may occur as a result of healthcare reform. This FOA provides support for up to two years (R21 phase) for research planning activities and feasibility studies, followed by possible transition of up to four years of expanded research support (R33 phase). The total project period for an application submitted in response to this FOA may not exceed five years.
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